Carbazoles: Role and Functions in Fighting Diabetes

Carbazole derivatives have gained a lot of attention in medicinal chemistry over the last few decades due to their wide range biological and pharmacological properties, including antibacterial, antitumor, antioxidant, anti-inflammatory activities. The therapeutic potential natural, semi-synthetic or synthetic carbazole-containing molecules has expanded considerably owing role pathogenesis development diabetes. Several studies demonstrated ability carbazole reduce oxidative stress, block adrenergic hyperactivation, prevent damage pancreatic cells modulate carbohydrate metabolism. In this survey, we summarize latest advances natural compounds involved diabetes pathways.